A Signaling View into the Inflammatory Tumor Microenvironment

The development of tumors requires an initiator event, usually exposure to DNA damaging agents that cause genetic alterations such as gene mutations or chromosomal abnormalities, leading to deregulated cell proliferation.Although the mere stochastic accumulation of further mutations may cause tumor progression, it is now clear that an inflammatory

read more


Use of Selective Serotonin Reuptake Inhibitor and Midodrine in a Patient With Autonomic Instability 2/2 Compressive Squamous Cell Carcinoma and Pain

A rare cause of reflex syncope is metastatic cancers involving the head and neck.These can irritate the glossopharyngeal nerve and lead to glossopharyngeal neuralgia with associated syncope.This type of syncope is difficult to treat since it commonly involves both a vasodepressor and cardioinhibitory response, and typically requires removal of the

read more